Wisconsin Legislature: DHS 115.04(4)(a)

DHS 115.01 Authority and purpose.

DHS 115.02 Applicability.

DHS 115.03 Definitions.

DHS 115.04 Congenital disorders.

DHS 115.05 Laboratory tests.

DHS 115.06 Criteria for adding or deleting conditions.

Note: Chapter HSS 115 was created as an emergency rule effective November 1, 1992. Chapter HSS 115 was renumbered ch. HFS 115 under s. 13.93 (2m) (b) 1., Stats., and corrections were made under s. 13.93 (2m) (b) 6. and 7., Stats, Register, May, 1998, No. 509. Chapter HFS 115 was renumbered chapter DHS 115 under s. 13.92 (4) (b) 1., Stats., and corrections made under s. 13.92 (4) (b) 7., Stats., Register January 2009 No. 637.

DHS 115.01 Authority and purpose. This chapter is promulgated under the authority of ss. 253.13 and 227.11 (2), Stats., to specify the congenital disorders for which each newborn is screened and tested.

History: Cr. Register, May, 1993, No. 449, eff. 6-1-93; correction made under s. 13.93 (2m) (b) 7., Stats., Register, July, 1995, No. 475; CR 14-074: am. Register July 2015 No. 715, eff. 8-1-15; EmR1920: emerg. am., eff. 10-15-19; CR 19-064: am Register December 2019 No. 768, eff. 1-1-20.

DHS 115.02 Applicability. This chapter applies to the attending physician licensed under ch. 448, Stats., nurse-midwife certified under s. 441.15, Stats., or other attendant at the birth of an infant born in Wisconsin, to the infant and the infant’s parents or guardian, and to the state laboratory.

History: Cr. Register, May, 1993, No. 449, eff. 6-1-93; CR 14-074: am. Register July 2015 No. 715, eff. 8-1-15.

DHS 115.03 Definitions. In this chapter:

(1) “Congenital disorder” means a disorder present at birth, either inherited or due to an influence occurring during gestation up to birth.

(2) “Department” means the Wisconsin department of health services.

(3) “ICD-10-CM” means the International Classification of Diseases, 10th Revision, Clinical Modification.

(4) “Medical consultant” means a physician licensed to practice medicine or osteopathy under ch. 448, Stats., who has expertise in treatment of one or more of the conditions listed under s. DHS 115.04.

(5) “Metabolic disorder” means a disorder of the chemical processes that take place in the body.

(6) “Screening” means checking each member of a population to identify presumptive medical conditions that indicate that diagnostic testing for congenital or metabolic disorders is needed.

(7) “State laboratory” means the state laboratory of hygiene under s. 36.25 (11), Stats.

History: Cr. Register, May, 1993, No. 449, eff. 6-1-93; correction in (2) made under s. 13.92 (4) (b) 6., Stats., Register January 2009 No. 637; CR 14-074: am. (3) Register July 2015 No. 715, eff. 10-1-15.

DHS 115.04 Congenital disorders. Pursuant to s. 253.13 (1), Stats., blood samples taken from each newborn shall be tested for all of the following conditions:

(1)

(a) Phenylketonuria (PKU), ICD-10-CM-E70.0.

(b) Hyperphenylalaninemia, ICD-10-CM-E70.1.

(2) Galactosemia, ICD-10-CM-E74.21.

(3) Congenital hypothyroidism, ICD-10-CM-E03.1.

(4) Hemoglobinopathies, including all of the following:

(a) Sickle cell disease, ICD-10-CM-D57.1.

(b) Hemoglobin S-beta Thalassemia, ICD-10-CM-D57.40.

(d) Hemoglobin disease other, ICD-10-CM-D58.2.

(5) Biotinidase deficiency, ICD-10-CM-D81.810.

(6) Congenital adrenal hyperplasia, ICD-10-CM-E25.0.

(7) Cystic fibrosis, ICD-10-CM-E84.9.

(8) Fatty acid oxidation disorders, including all of the following:

(a) Medium-chain acyl-CoA dehydrogenase deficiency, ICD-10-CM-E71.311.

(b) Long-chain L-3-Hydroxy acyl-CoA dehydrogenase deficiency, ICD-10-CM-E71.318.

(cm) Carnitine palmitoyltransferase IA deficiency, ICD-10-CM-E71.318.

(d) Carnitine palmitoyltransferase II deficiency, ICD-10-CM-E71.318.

(e) Carnitine-acylcarnitine translocase deficiency, ICD-10-CM-E71.318.

(f) Glutaric acidemia type II, ICD-10-CM-E71.313.

(g) 2, 4-Dienoyl-CoA reductase deficiency, ICD-10-CM-E71.318.

(h) Carnitine uptake defect, ICD-10-CM-E71.41.

(i) Medium/short-chain hydroxy CoA dehydrogenase deficiency, ICD-10-CM-E71.318.

(j) Medium-chain ketoacyl-CoA thiolase deficiency, ICD-10-CM-E71.318.

(9) Maple Syrup Urine Disease, ICD-10-CM-E71.0.

(10) Homocystinuria, ICD-10-CM-E72.11.

(11) Tyrosinemia types I, II, and III, ICD-10-CM-E70.21.

(12) Citrullinemia types I and II, ICD-10-CM-E72.23.

(13) Argininosuccinic acidura, ICD-10-CM-E72.22.

(14) Severe Combined Immunodeficiency and related conditions of immunodeficiency, ICD-10-CM-D81.9.

(15) Organic acidemias, including all of the following:

(a) Glutaric acidemia type I, ICD-10-CM-E72.3.

(b) Propionic acidemia, ICD-10-CM-E71.121.

(d) Isovaleric acidemia, ICD-10-CM-E71.110.

(e) 3-Methylcrotony1-CoA carboxylase deficiency, ICD-10-CM-E71.19.

(f) Multiple carboxylase deficiency, ICD-10-CM-D81.818.

(g) 3-Methylglutaconic aciduria, ICD-10-CM-E71.111.

(h) beta-Ketothiolase deficiency, ICD-10-CM-E71.19.

(i) 2-Methyl-3-hydroxbutyric aciduria, ICD-10-CM-
E71.19.

(j) 3-Hydroxy-3-methylglutaric aciduria, ICD-10-CM-
E71.118.

(15m) Spinal muscular atrophy, ICD-10-CM-G12.9.

(16) Critical congenital heart disease, including all of the following:

(a)

1. Coarctation of the aorta, ICD-10-CM-Q25.1.

2. Atresia of aorta, ICD-10-CM-Q25.2.

3. Stenosis of aorta, ICD-10-CM-Q25.3.

(b)

1. Double outlet right ventricle, ICD-10-CM-Q20.1.

2. Double outlet left ventricle, ICD-10-CM-Q20.2.

(d)

1. Hypoplastic left heart syndrome ICD-10-CM-Q23.4.

2. Congenital mitral stenosis or atresia, ICD-10-CM-Q23.2.

(e)

1. Interrupted aortic arch, ICD-10-CM-Q25.4.

2. Atresia of aorta, ICD-10-CM-Q25.2.

3. Stenosis of aorta, ICD-10-CM-Q25.3.

(f)

1. Pulmonary valve atresia, ICD-10-CM-Q22.0.

2. Other congenital malformations of the pulmonary valve, ICD-10-CM-Q22.3.

3. Atresia of pulmonary artery, ICD-10-CM-Q25.5.

(g) Single ventricle heart disease variants other than HLHS, including all of the following:

1. Hypoplastic right heart syndrome, ICD-10-CM-Q22.6.

2. Other congenital malformations of the tricuspid valve ICD-10-CM-Q22.8.